DBL Magnesium Sulfate

DBL Magnesium Sulfate

magnesium sulfate

Manufacturer:

Pfizer

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Mg sulfate
Indications/Uses
Acute hypomagnesaemia. Prevention of hypomagnesaemia in patients receiving TPN. Prevention & treatment of life-threatening seizures in treatment of pregnancy toxemias (preeclampsia & eclampsia).
Dosage/Direction for Use
Adult Mild hypomagnesaemia 1 g IM every 6 hr for 4 doses. Severe hypomagnesaemia 0.25 g/kg IM over 4 hr or 5 g slow IV infusion over 3 hr. TPN 0.5-3 g daily. Pregnancy toxemia Initially 4 g IV, followed by 4-5 g IM into each buttock or 1-2 g/hr infusion. May be followed by 4-5 g into alternate buttock every 4 hr. Infant TPN 0.25-1.25 g daily.
Contraindications
Heart block. Renal failure (CrCl <20 mL/min). Not to be used during pregnancy 2 hr prior to delivery.
Special Precautions
May precipitate acute myasthenic crisis. Monitor serum Mg levels at periodic intervals & urine output during 4 hr preceding dosing. Patellar reflex testing should be done prior to administering repeated dose. Determination of respiration rate prior to each dose. Renal impairment. Not to be given during pregnancy 2 hr prior to delivery. Lactation.
Adverse Reactions
Hypermagnesaemia eg, nausea, vomiting, flushing, hypotension, muscle weakness & paralysis, blurred or double vision, CNS depression & loss of reflexes; hypocalcemia. Inj site irritation & pain.
Drug Interactions
Heart block w/ cardiac glycosides/digitalis. Enhanced CNS depressant effect. Excessive neuromuscular blockade w/ neuromuscular blocking agents. Exaggerated hypotensive response w/ nifedipine. Precipitation w/ Ca salts. Incompatibility w/ alkali carbonates, bicarbonates & soluble phosphates.
MIMS Class
ATC Classification
B05XA05 - magnesium sulfate ; Belongs to the class of electrolyte solutions used in I.V. solutions.
Presentation/Packing
Form
DBL Magnesium Sulfate inj 49.3 %
Packing/Price
5 mL x 10 × 1's
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