Deferasirox - oral

Patient Medicine Information
Why do I need this medicine?
Deferasirox is used to remove excess iron in your body. Iron may build up in your body after repeated blood transfusions.
How do I take this medicine?
Take Deferasirox exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Deferasirox is available as a tablet or as a tablet for oral suspension.

Take this medicine on an empty stomach, at least 30 minutes before meals. Try to take it at the same time each day.

If you have been given the tablet for oral suspension, disperse the tablet in a glass of water, orange or apple juice. Stir it well until a fine suspension is obtained. Drink the entire contents immediately. Do not chew or swallow the tablet.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:

- result of kidney function test and platelet count that are not within the normal limit
- at high risk of tumour
- inability to perform basic activities such as getting dressed, eating, and bathing
as Deferasirox may not be suitable for you.

What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:

- kidney disease
- liver disease
- blood disorder

Let your doctor know if you are pregnant or breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.

- Your doctor may need to do routine blood tests while you are being treated with Deferasirox.
- Tests for your kidney and liver function may be performed.
- An eye examination and a test for your sense of hearing may also be done.
What side effects could I experience?
Deferasirox may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: fever, headache, nausea, vomiting, diarrhoea, stomach pain, rashes, cough and sore throat.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- decreased red blood cell, white blood cell or platelet count
- bleeding or irritation of the stomach or intestine
- yellowing of the skin or eyes, decreased urine output
- decreased hearing
- increased pressure in the eye
- clouding of the lens of the eyes
- swollen eyes
- breathlessness
- rashes with skin peeling or blister

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines for neutralising stomach acid e.g. antacids containing aluminium
- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenobarbital, phenytoin
- cholesterol-lowering medicines e.g. colestyramine, simvastatin
- medicines for mood disorders e.g. midazolam
- medicines for asthma e.g. theophylline
- medicines for diabetes e.g. repaglidine
- medicines for tuberculosis (TB) e.g. rifampicin
- medicines for HIV infection e.g. ritonavir
- medicines used in organ transplant or certain immune disorders e.g. ciclosporin

This list does not include all medicines that may interact with Deferasirox.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on deferasirox - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by
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