Degarelix - subcutaneous

Patient Medicine Information
Why do I need this medicine?
Degarelix is used to treat men with prostate cancer that has spread to other parts of the body.
How do I use this medicine?
Your doctor or nurse will administer the injection for you.

Degarelix is to be injected subcutaneously (into the fatty layer under the skin) in the stomach area.

Make sure your injection site is free from any pressure (e.g. belts, waistbands or other types of clothing). Do not rub or scratch the injection site.

The injection site will vary each time you receive a dose of Degarelix.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on your condition.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Degarelix.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Do not use Degarelix if you ever had an allergic reaction (rashes, breathlessness, swollen eyes) to this medicine.

Degarelix is not for use in women. This medicine must not be given to pregnant or breastfeeding women.
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • heart disease e.g. history of heart rhythm disorder, or at risk for heart rhythm problems e.g. heart failure, electrolyte imbalance (imbalance of minerals in the body)
  • diabetes
  • kidney disease
  • liver disease
  • osteoporosis (brittle bones), or any condition that affects the strength of your bones
If you are going for certain diagnostic tests, inform your doctor that you are on Degarelix treatment.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • You may need to have routine blood tests (e.g. prostate-specific antigen, testosterone, electrolyte) while you are being treated with Degarelix.
  • Regular monitoring of heart and liver function may also be needed. Your doctor will advise you on how often you will need to have these tests.
What side effects could I experience?
Degarelix may cause dizziness or tiredness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects may include any of the following: weight gain, nausea, constipation, diarrhoea, chills, fever, back pain, breast enlargement, erection problems, hot flushes, excessive sweating, and injection site pain, redness or swelling.

If you develop rashes, breathlessness, swollen mouth or eyes, inform your doctor quickly. These could be signs of an allergic reaction.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience fast or irregular heartbeat.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for heart disease e.g. amiodarone, dofetilide, ibutilide, sotalol, disopyramide, quinidine
  • medicines for mood disorder
  • methadone (medicine for pain relief and part of drug addiction detoxification)
  • moxifloxacin (an antibiotic)
This list does not include all medicines that may interact with Degarelix.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

As this is a cancer medicine, unused or expired medicine must be returned to the clinic, hospital or pharmacy for disposal.
This information is independently developed by MIMS based on degarelix - subcutaneous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2023 MIMS. All rights reserved. Powered by
  • Firmagon
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in