Not a protection against HIV infection or other STDs. Not recommended in patients w/ history of venous thromboembolism (VTE). Unexpected vag bleeding, degree of fluid retention, history of clinical depression treatment, diabetic patients; diplopia, sudden partial or complete loss of vision, proptosis; loss of bone mineral density; osteoporotic risk factors eg, chronic alcoholism/tobacco use, chronic use of drugs reducing bone mass eg, anticonvulsants or corticosteroids, low BMI, eating disorder eg, anorexia nervosa or bulimia, metabolic bone disease, strong family history of osteoporis; breast & ovarian cancer; increased risk of CV events eg, MI, CHD, stroke, VTE; CAD; stroke; pulmonary embolism; dementia. Ensure adequate calcium & vit D intake. Hepatic insufficiency. Lactation. Pre-menarche childn.