Dermovate

Dermovate

clobetasol

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Clobetasol propionate
Indications/Uses
Relief of inflammatory & pruritic manifestations of steroid-responsive dermatoses eg, psoriasis (excluding widespread plaque psoriasis), recalcitrant dermatoses, lichen planus, discoid lupus erythematosus & other conditions which do not respond satisfactorily to less active steroids.
Dosage/Direction for Use
Adult, elderly & childn >1 yr Apply to affected area once or bd for up to 4 wk. Max: Not to exceed 50 g wkly. Patient who frequently relapse Reduce to once daily twice wkly.
Contraindications
Untreated cutaneous infections, rosacea, acne vulgaris, pruritus w/o inflammation, perianal & genital pruritus, perioral dermatitis. Dermatoses in childn <1 yr including dermatitis.
Special Precautions
Hypersensitivity to corticosteroids. Cushing's syndrome & reversible hypothalamic-pituitary-adrenal axis suppression. Increased risk of systemic effects. Concomitant infection. Psoriasis; chronic leg ulcers. Use w/ occlusive dressings. Avoid contact w/ face & eyes. Avoid abrupt w/drawal. Renal or hepatic impairment. Pregnancy & lactation. Avoid long-term continuous therapy in childn <12 yr. Elderly.
Adverse Reactions
Pruritus, local skin burning/skin pain.
Drug Interactions
Inhibited metabolism by CYP3A4 inhibitors eg, ritonavir & itraconazole.
MIMS Class
Topical Corticosteroids
ATC Classification
D07AD01 - clobetasol ; Belongs to the class of very potent (group IV) corticosteroids. Used in the treatment of dermatological diseases.
Presentation/Packing
Form
Dermovate cream 0.05%
Packing/Price
100 g x 1's (RM89.05/tube);15 g x 1's (RM25.95/tube)
Form
Dermovate oint 0.05%
Packing/Price
100 g x 1's (RM89.05/tube);15 g x 1's (RM25.95/tube)
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