Discontinue use if difficulty in breathing, upper airway obstruction or fall in BP & anticholinergic CNS effects occur. Patients w/ clinically significant bladder outflow obstruction at risk of urinary retention, GI obstructive disorders at risk of gastric retention, decreased GI motility or patients being treated for narrow-angle glaucoma. Myasthenia gravis; history of QT prolongation. Concomitant use w/ class IA or III antiarrhythmics. May affect ability to drive or operate heavy machinery. Not recommended in severe hepatic impairment & CrCl <10 mL/min. Pregnancy & lactation. Ped.