Diethylamine salicylate

Generic Medicine Info
Indications and Dosage
Musculoskeletal pain
Adult: As 10% w/w cream: Apply onto the affected area 2 or 3 times daily. Use sparingly.
Child: ≥6 years Same as adult dose.
Hypersensitivity to diethylamine salicylate, aspirin, or other NSAIDs (including oral hypersensitivity) particularly when associated with history of asthma. Application on broken, abraded, or cut skin.
Special Precautions
Patient with asthma. Children. Pregnancy and lactation.
Adverse Reactions
Skin and subcutaneous tissue disorders: Temporary skin reactions (e.g. rashes, redness, discomfort, irritation, burning sensation).
Patient Counseling Information
Avoid contact with eyes and sensitive skin areas.
Drug Interactions
May enhance the anticoagulant effects of warfarin. May increase the blood concentrations and risk of toxicity of methotrexate.
Mechanism of Action: Diethylamine salicylate is a salicylic acid derivative topical analgesic. It has the anti-inflammatory effects of salicylates and may be used as a counterirritant.
Absorption: Absorbed through the skin (small amounts as salicylic acid).
Excretion: Via urine.
Chemical Structure

Chemical Structure Image
Diethylamine Salicylate

Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 9837223, Diethylamine salicylate. Accessed Oct. 26, 2020.

Store below 25°C.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Algesal Cream (Thornton & Ross Limited). MHRA. Accessed 02/10/2020.

Anon. Diethylamine Salicylate. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. Accessed 02/10/2020.

Buckingham R (ed). Diethylamine Salicylate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. Accessed 02/10/2020.

Odour Free Lloyds Cream (Thornton & Ross Limited). MHRA. Accessed 02/10/2020.

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