Difflam-C Solution should generally be used undiluted, but if stinging occurs it may be diluted with water. The solution should be expelled from the mouth after use. Uninterrupted treatment should not exceed seven days.
Dosage in Adults: When used as a gargle, the usual dose is 15mL (approximately one tablespoon) which should be gargled for at least 30 seconds at 1½ to 3 hourly intervals, as needed. When used as a rinse for oral lesions, the usual dose is 15mL (approximately one tablespoon) which should be held in the mouth and swirled around for at least 30 seconds with repeat use every 1½ to 3 hours throughout the day. Chlorhexidine in Difflam-C Solution helps to reduce the development of plaque and gingivitis during the period of treatment when usual oral hygiene measures are interrupted. If used as an alternate to usual oral hygiene procedures, Difflam-C Solution should be swirled around in the mouth for at least a minute.
Difflam-C Solution is best used after brushing the teeth to minimise chlorhexidine induced discolouration. Difflam-C Solution is not intended for prolonged use except under dental or medical supervision.
Dosage in Children: 5 to 15mL as a gargle if able to do so, or as an oral rinse.
With Impaired Renal Function: Since absorbed benzydamine and its metabolites are excreted in the urine, the possibility of systemic effects should be considered in patients with severe renal impairment.
With Impaired Liver Function: Since absorbed benzydamine is highly metabolised in the liver, possibility of systemic effects should be considered in patients with severe hepatic impairment.