Confirm the patient is not pregnant before starting the treatment.
Hypersensitivity to GnRH, its analogues or to any of the excipients.
3.75 mg: Diphereline P.R. 3.75 mg should never be used during pregnancy and breast feeding.
In the pre-menopausal breast cancer setting: Initiation of aromatase inhibitor treatment before adequate ovarian suppression with triptorelin has been achieved.
11.25 mg: Diphereline P.R. should never be used in pregnancy.