Duac

Duac

clindamycin + benzoyl peroxide

Manufacturer:

Stiefel

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Per g Clindamycin 10 mg, benzoyl peroxide 50 mg
Indications/Uses
Mild to moderate acne vulgaris particularly inflammatory lesions.
Dosage/Direction for Use
Adult & adolescent ≥12 yr Apply once daily to affected area in the evening. Max duration: Not >12 wk of continuous use.
Contraindications
Hypersensitivity to clindamycin, lincomycin, benzoyl peroxide.
Special Precautions
Discontinue use if severe local irritation occurs. History of regional enteritis, ulcerative colitis, antibiotic-associated colitis. Clostridium difficile-associated diarrhoea. Cross-resistance. Atopic patients. Avoid prolonged sun exposure. Avoid contact w/ mouth, eyes, lips, other mucous membranes, irritated or broken skin. Recent history of systemic or topical clindamycin or erythromycin use. Pregnancy & lactation. Not recommended in childn <12 yr.
Adverse Reactions
Erythema, peeling, dryness. Burning sensation.
Drug Interactions
Cumulative irritant effect w/ other topical antibiotics, medicated or abrasive soaps & cleansers, soaps & cosmetics w/ strong drying effect & products w/ high alcohol &/or astringents conc. Possible antagonism w/ erythromycin-containing products. Enhanced action of other neuromuscular-blocking agents. Reduced efficacy & increased irritation w/ tretinoin, isotretinoin & tazarotene. Temporarily change of skin & facial hair colour w/ sulfonamide-containing topical products.
ATC Classification
D10AF51 - clindamycin, combinations ; Belongs to the class of topical antiinfective preparations used in the treatment of acne.
Presentation/Packing
Form
Duac topical gel
Packing/Price
25 g x 1's (RM85/tube)
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