ipratropium + fenoterol


Boehringer Ingelheim


Concise Prescribing Info
Per 4 mL Ipratropium Br 0.5 mg, fenoterol HBr 1.25 mg
Prevention & treatment of symptoms in chronic obstructive airway disorders w/ reversible airflow limitation eg, bronchial asthma & especially chronic bronchitis w/ or w/o emphysema. Concomitant anti-inflammatory therapy considered for patients w/ bronchial asthma & steroid responsive COPD.
Dosage/Direction for Use
Adult, elderly & adolescent >12 yr Acute asthma episodes 1 unit-dose vial. Very severe cases 2 unit-dose vials.
Hypersensitivity to fenoterol HBr or atropine-like substances. Hypertrophic obstructive cardiomyopathy & tachyarrhythmia.
Special Precautions
Hypersensitivity. Discontinue immediately if paradoxical bronchospasm occurs. Acute, rapidly worsening dyspnoea. Patients predisposed to narrow-angle glaucoma, insufficiently controlled DM, recent MI, severe organic heart or vascular disorders, severe CV disease, hyperthyroidism, phaeochromocytoma, preexisting urinary outflow tract obstruction (eg, prostatic hyperplasia or bladder-neck obstruction). Hypokalaemia, cystic fibrosis. Prolonged use. May affect ability to drive & use machines. Pregnancy & lactation. Not recommended in childn ≤12 yr.
Adverse Reactions
Cough, dry mouth, headache, tremor, pharyngitis, nausea, dizziness, dysphonia, tachycardia, palpitations, vomiting, increased systolic BP & nervousness.
Drug Interactions
Enhanced bronchodilatatory effects w/ other β-adrenergics, anticholinergics & xanthine derivatives eg, theophylline. Potentially serious reduction in bronchodilatation w/ β-blockers. Increased β2-agonist induced hypokalaemia w/ corticosteroids & diuretics. Increased susceptibility to arrhythmias w/ digoxin. Enhanced β-adrenergic agonists action w/ MAOIs & TCAs. Increased susceptibility to CV effects of β-agonists w/ halogenated hydrocarbon anaesth eg, halothane, trichloroethylene & enflurane.
ATC Classification
R03AL01 - fenoterol and ipratropium bromide ; Belongs to the class of combination of adrenergics with anticholinergics, that may also include a corticosteroid. Used in the treatment of obstructive airway diseases.
Duovent inhalant (unit-dose vial)
4 mL x 60 × 1's
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