Dupilumab is used on its own or together with topical anti-inflammatory medicines to treat atopic dermatitis (a skin condition that causes red and itchy rashes).
This medicine may also be used together with other medicines to treat asthma.
Dupilumab is to be injected subcutaneously (into the fatty layer under the skin, usually in the thigh, upper arm or abdomen area).
Your doctor or nurse will administer the injection for you. If you or your caregiver had been given the proper training on the preparation and injection techniques of this medicine, you or your caregiver may do the administration.
Remember to rotate the injection sites. Do not inject into the same area all the time. New injection sites should be at least 1.5 inches away from the previous injection site. Do not inject near the navel (belly button).
Do not administer this medicine into skin that is tender, damaged, bruised or scarred.
This medicine is available as a pre-filled pen or syringe. Make sure you know how to use the specific device you have been given. If you have problems or do not understand the instructions, ask your doctor or pharmacist.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
This medicine must be administered regularly for it to be effective. Continue using Dupilumab even when you feel better. Do not stop using it unless instructed by the doctor.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Dupilumab.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
If you or a caregiver had been trained to administer this medicine, administer the injection within 7 days from the missed dose and return to your normal dosing schedule. If the missed dose is not administered within 7 days, wait until the next dose on the original schedule.
DO NOT double a dose under any circumstances.
Inform your doctor or pharmacist immediately if you forgot to administer your dose.
Alert your doctor if you have been recently vaccinated.
You must avoid any vaccinations without consulting with your doctor.
Inform your doctor if you have infections caused by parasites.
If you have asthma and are being treated for atopic dermatitis, notify your doctor.
Let your doctor know if you are pregnant or breastfeeding.
Dupilumab may cause any of the following side effects: headache, injection site reactions (e.g. erythema, swelling, pain, pruritus) and dry eyes.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- rashes, breathlessness, swelling of the face, eyes or mouth
- conjunctivitis (redness and inflammation of the membranes covering the white part of eyes)
- keratitis (inflammation of the cornea of the eye)
- pins and needles or numbness of arms or legs, flu-like illness
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Avoid vaccinations with live vaccines during treatment with Dupilumab.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in a refrigerator, between 2-8°C. May store in a cool, dry place for up to 14 days only.
Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.
Do not shake.
Protect from light by keeping it inside the carton.
If you notice that the injection has changed colour or has become cloudy, do not use it. Throw it away and use a new injection.
Medicines must not be used past the expiry date.
This medicine should not be thrown in the household waste. Ask your doctor or pharmacist how to properly dispose this medicine.