Edyfil

Edyfil Dosage/Direction for Use

sildenafil

Manufacturer:

Y.S.P. Industries

Distributor:

Y.S.P. Industries
Full Prescribing Info
Dosage/Direction for Use
Adults: The recommended dose is 50 mg taken, as needed, approximately 1 hr before sexual activity. Based on effectiveness and tolerance, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. The maximum recommended daily dose is 100 mg. The maximum recommended dosing frequency is once per day.
Elderly: Dosage adjustments are not required in elderly patients.
Children: Sildenafil is not indicated for use in children (<18 years).
Patients with Impaired Renal Function: Dosage adjustments are not required in patients with mild to moderate renal impairment (creatinine clearance = 30-80 mL/min).
Since sildenafil clearance is reduced in patients with severe renal impairment (creatinine clearance <30 mL/min), a 25-mg dose should be considered.
Patients with Impaired Hepatic Function: Since sildenafil clearance is reduced in patients with hepatic impairment (eg, cirrhosis), a 25-mg dose should be considered.
Patients Using Other Medicines: Given the extent of the interaction with patients receiving concomitant therapy with ritonavir, it is recommended not to exceed a maximum single dose of 25 mg sildenafil in a 48-hr period. A starting dose of 25 mg should be considered in patients receiving concomitant treatment with CYP3A4 inhibitors eg, erythromycin, saquinavir, ketoconazole, itraconazole.
In order to minimize the potential for developing postural hypotension, patients should be stable on α-blocker therapy prior to initiating sildenafil treatment. In addition, initiation of sildenafil at lower doses should be considered.
Mode of Administration: For oral administration.
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