Elthrocin Tablet

Elthrocin Tablet

erythromycin

Manufacturer:

SM Pharmaceuticals

Distributor:

SM Pharmaceuticals
Concise Prescribing Info
Contents
Erythromycin stearate
Indications/Uses
Upper & lower resp tract, ear & oral, eye, veneral, skin & soft tissue, GI infections. Osteomyelitis, diphtheria, scarlet fever, pertussis. Prophylaxis of pre- & post-op, trauma, burns, rheumatic fever, bacterial endocarditis.
Dosage/Direction for Use
Adult Mild to moderate infection 250 mg every 6 hr or 500 mg every 12 hr. Very severe infection Up to ≥4 g daily. Childn 30 mg/kg daily in divided doses. Very severe infection 50 mg/kg or 100 mg/kg daily in 2 or 3 divided doses. Upper & lower resp tract infection Duration: 6-10 days. β-haemolytic Streptococci group A infection Duration: 10 days. Mycoplasma pneumoniae infection Duration: 10-14 days. Acne 1 g daily for 1-2 wk. Min: 0.5 g daily for 12 wk. Impetigo 1 g daily for 10 days. Erysipelas, phlegmon, furunculosis, carbuncles 2 g daily for 10 days. Erythrasma 1.5 g daily for 6 days. Otitis externa 1.5 g daily for 6-10 days. Nonspecific urethritis 1.5-2 g daily for 14-21 days. Syphilis 3 g daily in divided doses for 10-20 days. Lymphogranuloma venereum 1.5 g daily for 8-10 days. Gingivitis 1 g daily for 6-10 days. Diphtheria, scarlet fever 1-1.5 g daily for 10 days. Trachoma 1.5 g daily for 21 days. Pre-op prophylaxis 1 g 1 hr before procedure followed by 500 mg 6 hr after.
Administration
Should be taken on an empty stomach: Best taken on an empty stomach 1 hr before or 2 hr after meals. May be taken w/ meals to reduce GI discomfort.
Contraindications
Hypersensitivity. Co-administration w/ astemizole or terfenadine. Concurrent use w/ potentially hepatotoxic drugs. Avoid use in patients w/ existing liver dysfunction.
Special Precautions
History of cardiac arrhythmias or QT prolongation & hearing loss. Superinfection; acute porphyria. Renal or hepatic impairment. Pregnancy & lactation. Elderly.
Adverse Reactions
GI disturbances eg, abdominal or stomach discomfort & cramp, nausea, vomiting & diarrhoea.
Drug Interactions
Increased serum theophylline & digoxin conc. Decreased plasma clearance & prolonged duration of action of alfentanil. Inhibited carbamazepine & valproic acid metabolism. Antagonized effects of chloramphenicol or lincomycin. Increased cyclosporine plasma conc. Increased vasospasm associated w/ ergotamine. Increased risk of rhabdomyolysis w/ lovastatin. Decreased clearance of midazolam or triazolam. Increased potential for ototoxicity w/ other ototoxic medications. Increased risk of hemorrhage w/ warfarin.
MIMS Class
ATC Classification
J01FA01 - erythromycin ; Belongs to the class of macrolides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Elthrocin FC tab 500 mg
Packing/Price
10 × 10's
Form
Elthrocin FC tab 250 mg
Packing/Price
100 × 10's
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