Generic Medicine Info
Indications and Dosage
Seasonal allergic conjunctivitis
Adult: As 0.05% emedastine difumarate soln: Instill 1 drop to the affected eye(s) up to 4 times daily.
Child: ≥3 yr Same as adult dose.
Special Precautions
Lactation. Not indicated for contact lens-related irritation.
Adverse Reactions
Significant: Corneal infiltrates.
Nervous: Headache, asthenia, abnormal dreams.
GI: Dysgeusia.
Ophthalmologic: Blurred vision, ocular burning, stinging, discomfort, dryness, pruritus, and hyperemia; corneal staining, foreign body sensation, keratitis, lacrimation.
Resp: Rhinitis, sinusitis.
Dermatologic: Dermatitis.
Patient Counseling Information
This drug may cause blurred vision or other visual disturbances, if affected, do not drive or operate machinery.
Mechanism of Action: Emedastine is a selective histamine (H1) receptor antagonist for ophthalmic use.
Absorption: Minimally absorbed.
Excretion: Elimination half-life: 10 hr.
Chemical Structure

Chemical Structure Image

Source: National Center for Biotechnology Information. PubChem Database. Emedastine, CID=3219, https://pubchem.ncbi.nlm.nih.gov/compound/Emedastine (accessed on Jan. 22, 2020)

Store between 4-30°C.
MIMS Class
Ophthalmic Decongestants, Anesthetics, Anti-Inflammatories
ATC Classification
S01GX06 - emedastine ; Belongs to the class of other ophthalmologic antiallergics.
Anon. Emedastine. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 02/03/2017.

Buckingham R (ed). Emedastine Fumarate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 02/03/2017.

Emadine Solution/Drops (Alcon Laboratories, Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 02/03/2017.

Joint Formulary Committee. Emedastine. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 02/03/2017.

McEvoy GK, Snow EK, Miller J et al (eds). Emedastine Difumarate (EENT). AHFS Drug Information (AHFS DI) [online]. American Society of Health-System Pharmacists (ASHP). https://www.medicinescomplete.com. Accessed 02/03/2017.

Disclaimer: This information is independently developed by MIMS based on Emedastine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2023 MIMS. All rights reserved. Powered by MIMS.com
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