Enoxacin


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO UTI 200-400 mg twice daily. Uncomplicated gonorrhoea 400 mg as a single dose.
Dosage Details
Oral
Urinary tract infections
Adult: 200-400 mg bid.

Oral
Uncomplicated gonorrhoea
Adult: 400 mg as a single dose.
Administration
Should be taken on an empty stomach. Take 1 hr before or 2 hr after meals w/ full glass of water. Ensure adequate fluid intake daily. Avoid caffeine.
Contraindications
Hypersensitivity; lactation; child; adolescent; pregnancy.
Special Precautions
Impaired hepatic or renal function; G6PD deficiency; myasthenia gravis; maintain adequate fluid intake; avoid excessive alkalinity of the urine, exposure to strong sunlight/sunlamp; epilepsy; history of CNS disorders. Discontinue in case of tendon pain, inflammation or rupture. May impair ability to drive and operate machinery. High level of resistance with Staph. aureus infections.
Adverse Reactions
GI disturbances; CNS effects; hypersensitivity-type reactions; reversible arthralgia; hepatic effects; haematological disturbances; tachycardia; superinfection; pain and irritation at Inj site; tendon damage; phlebitis and thrombophloebitis.
Drug Interactions
May inhibit hepatic metabolism and clearance of drugs metabolized in the liver eg theophylline and caffeine; antacids and metal cations; antineoplastics.
Lab Interference
Elevated liver enzyme values.
Action
Description: Enoxacin inhibits DNA gyrase and topoisomerase IV which are essential in bacterial DNA reproduction.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Enoxacin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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