Epitech

Epitech

levetiracetam

Manufacturer:

Global Pharmatech

Distributor:

Averroes Pharma
Concise Prescribing Info
Contents
Levetiracetam
Indications/Uses
Monotherapy for partial onset seizures w/ or w/o secondary generalisation & adolescents from 16 yr w/ newly diagnosed epilepsy. Adjunctive therapy in partial onset seizures w/ or w/o secondary generalisation in adults, adolescents & childn from 4 yr w/ epilepsy; myoclonic seizures in adults & adolescents from 12 yr w/ juvenile myoclonic epilepsy; primary generalised tonic-clonic seizures in adults & adolescents from 12 yr w/ idiopathic generalised epilepsy. Alternative for patients when oral administration is temporarily not feasible.
Dosage/Direction for Use
Monotherapy Adult & adolescent from 16 yr Initially 250 mg bd, may be increased to 500 mg bd after 2 wk. May be further increased by 250 mg bd every 2 wk depending on clinical response. Max: 1,500 mg bd. Add-on therapy Adult ≥18 yr & adolescent 12-17 yr, ≥50 kg Initially 500 mg bd started on 1st day of treatment, may be increased up to 1,500 mg bd. Dose changes can be made in 500 mg bd increases or decreases every 2-4 wk. Childn 4-11 yr & adolescent 12-17 yr, <50 kg Initially 10 mg/kg bd, may be increased up to 30 mg/kg bd. Dose changes should not exceed 10 mg/kg bd increases or decreases every 2 wk. Childn ≥50 kg Adult dose.
Contraindications
Hypersensitivity to levetiracetam or other pyrrolidone derivatives.
Special Precautions
Serious dermatological reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis. Behavioral abnormalities & psychotic symptoms; hematologic abnormalities; increased BP. Monitor for psychiatric signs & symptoms; coordination difficulties. Avoid abrupt w/drawal. May affect ability to drive & use machines. Acute kidney injury. Renal or severe hepatic impairment. Seizure control during pregnancy. Lactation.
Adverse Reactions
Nasopharyngitis; somnolence, headache. Anorexia; depression, hostility/aggression, anxiety, insomnia, nervousness/irritability; convulsion, balance disorder, dizziness, lethargy, tremor; vertigo; cough; abdominal pain, diarrhoea, dyspepsia, vomiting, nausea; rash; asthenia/fatigue.
MIMS Class
ATC Classification
N03AX14 - levetiracetam ; Belongs to the class of other antiepileptics.
Presentation/Packing
Form
Epitech infusion conc 100 mg/mL
Packing/Price
5 mL x 1's
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