Mild to moderately severe dementia associated w/ Alzheimer's or Parkinson's disease Start w/ Exelon Patch 5 once daily, may be increased to Exelon Patch 10 after min of 4 wk. Severe dementia associated w/ Alzheimer's disease Dosage may then be further increased to Exelon Patch 15.
Hypersensitivity to other carbamate derivatives. History of application site reactions suggestive of allergic contact dermatitis w/ rivastigmine transdermal patch.
If treatment is interrupted for >3 days, it should be re-initiated w/ Exelon Patch 5. Risk of dehydration in case of prolonged vomiting or diarrhoea. Induced or exacerbated extrapyramidal symptoms & worsening of parkinsonian symptoms by cholinomimetics. Monitor patient's wt during therapy. Sick-sinus syndrome, conduction defects (SA or AV block), gastroduodenal ulcerative conditions, history of or current resp disease, urinary obstruction, seizures in predisposed patients. Discontinue use in case of disseminated skin hypersensitivity. Carefully titrate dose & monitor patients <50 kg. Hepatic impairment. Pregnancy & lactation. Childn.
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