Exelon Patch

Exelon Patch

rivastigmine

Manufacturer:

Novartis

Distributor:

DKSH
Concise Prescribing Info
Contents
Rivastigmine
Indications/Uses
Mild to moderately severe dementia associated w/ Alzheimer's or Parkinson's disease & severe dementia associated w/ Alzheimer's disease.
Dosage/Direction for Use
Mild to moderately severe dementia associated w/ Alzheimer's or Parkinson's disease Start w/ Exelon Patch 5 once daily, may be increased to Exelon Patch 10 after min of 4 wk. Severe dementia associated w/ Alzheimer's disease Dosage may then be further increased to Exelon Patch 15.
Contraindications
Hypersensitivity to other carbamate derivatives. History of application site reactions suggestive of allergic contact dermatitis w/ rivastigmine transdermal patch.
Special Precautions
If treatment is interrupted for >3 days, it should be re-initiated w/ Exelon Patch 5. Risk of dehydration in case of prolonged vomiting or diarrhoea. Induced or exacerbated extrapyramidal symptoms & worsening of parkinsonian symptoms by cholinomimetics. Monitor patient's wt during therapy. Sick-sinus syndrome, conduction defects (SA or AV block), gastroduodenal ulcerative conditions, history of or current resp disease, urinary obstruction, seizures in predisposed patients. Discontinue use in case of disseminated skin hypersensitivity. Carefully titrate dose & monitor patients <50 kg. Hepatic impairment. Pregnancy & lactation. Childn.
Adverse Reactions
Nausea. Vomiting, anorexia, decreased appetite, anxiety, depression, insomnia, dizziness, headache, diarrhoea, dyspepsia, abdominal pain, urinary incontinence, application site reactions (erythema, pruritus, oedema), fatigue, asthenia, decreased wt, UTI.
Drug Interactions
Metoclopramide, cholinomimetic drugs, anticholinergic medications, succinylcholine-type muscle relaxants during anaesth; β-blockers.
ATC Classification
N06DA03 - rivastigmine ; Belongs to the class of anticholinesterases. Used in the management of dementia.
Presentation/Packing
Form
Exelon Patch transdermal patch 4.6 mg/24 hr
Packing/Price
30 × 1's
Form
Exelon Patch transdermal patch 13.3 mg/24 hr
Packing/Price
30 × 1's
Form
Exelon Patch transdermal patch 9.5 mg/24 hr
Packing/Price
30 × 1's
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