Discontinue use if allergic/hypersensitivity reactions including life-threatening Stevens-Johnson syndrome, toxic epidermal necrolysis, acute anaphylactic reaction/shock; gout flare occur. Not to be initiated until acute gout attack subsides completely. Avoid use in patients w/ pre-existing major CV diseases eg, MI, stroke or unstable angina. Not recommended in patients whom rate of urate formation is greatly increased; in organ transplant recipients. Exacerbation &/or onset of CV disease; thyroid function alteration. Perform liver function test prior to & periodically thereafter. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Not recommended in patients concomitantly treated w/ mercaptopurine/azathioprine. May affect ability to drive & use machines. Severe renal & moderate to severe hepatic impairment. Not to be used during pegnancy & lactation. Childn <18 yr.