Concise Prescribing Info
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Migraine prophylaxis; Prophylaxis of peripheral and cerebrovascular disorders; Prophylaxis of vertigo and vestibular disorders 5-10 mg/day at bedtime.
Dosage Details
Prophylaxis of migraine, Prophylaxis of peripheral and cerebrovascular disorders, Prophylaxis of vertigo and vestibular disorders
Adult: 5-10 mg daily at bedtime.
May be taken with or without food.
Pregnancy, lactation, GI or urinary tract obstruction, acute porphyrias.
Special Precautions
Driving or operating machinery, epilepsy, elderly, CVS disease, glaucoma.
Adverse Reactions
Drowsiness. Rarely wt gain, headache, depression, gastric pain, dry mouth, insomnia, extrapyramidal reactions, galactorrhoea.
Drug Interactions
Plasma levels reduced by phenytoin, carbamazepine, valproic acid.
Description: Flunarizine has H1-receptor blocking action and calcium-channel blocking effect. It has also been used as an adjunct epileptic therapy for patients refractory to standard treatment regimens.
Absorption: Absorbed well from the GI tract (oral).
Distribution: Highly lipophilic. Protein-binding: >90%.
Metabolism: Extensive.
Excretion: Via bile (as metabolites); 18 days (elimination half-life).
Store below 25°C.
Disclaimer: This information is independently developed by MIMS based on Flunarizine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
  • Migarid
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in