Fosrenol

Fosrenol

lanthanum carbonate

Manufacturer:

Takeda

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Lanthanum carbonate
Indications/Uses
Phosphate-binding agent for control of hyperphosphataemia in chronic renal failure patients on haemodialysis or continuous ambulatory peritoneal dialysis (CAPD) when Ca level is not controlled & where hyperparathyroidism is present & in adult patients w/ chronic kidney disease not on dialysis w/ serum phosphate levels ≥1.78 mmol/L in whom low phosphate diet alone is insufficient to control serum phosphate levels.
Dosage/Direction for Use
Adult including elderly >65 yr Control of serum phosphate level Initially 750 mg daily then 1,500-3,000 mg daily. Max: 3,750 mg daily.
Administration
Should be taken with food: Take w/ or immediately after meals. Chew thoroughly before swallowing. Do not swallow whole.
Contraindications
Hypersensitivity. Hypophosphataemia.
Special Precautions
Discontinue use if hypophosphataemia develops. Patients predisposed to GI obstruction, ileus, subileus & perforation including those w/ altered GI anatomy eg, diverticular disease, peritonitis, history of GI surgery, cancer & ulceration; hypomotility disorders eg, constipation, diabetic gastroparesis. Regularly monitor Ca serum levels & liver function tests. Long-term use. Glucose-galactose malabsorption. May affect ability to drive & use machines. Hepatic impairment. Not recommended during pregnancy. Lactation. Not recommended in childn & adolescents.
Adverse Reactions
Headache; abdominal pain, diarrhoea, nausea, vomiting. Hypocalcaemia; constipation, dyspepsia, flatulence.
Drug Interactions
Decreased bioavailability of oral ciprofloxacin. Reduced absorption of levothyroxine. Drugs known to interact w/ antacids eg, chloroquine, hydroxychloroquine, ketoconazole; tetracycline & doxycycline.
ATC Classification
V03AE03 - lanthanum carbonate ; Belongs to the class of drugs used in the treatment of hyperkalemia and hyperphosphatemia.
Presentation/Packing
Form
Fosrenol chewable tab 1,000 mg
Packing/Price
90's
Form
Fosrenol chewable tab 500 mg
Packing/Price
90's
Form
Fosrenol chewable tab 750 mg
Packing/Price
90's
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