Discontinue use if pancreatitis, severe & disabling arthralgia are suspected; jaundice or other signs of liver dysfunction develops. Not an insulin substitute. Not to be used in type 1 diabetes or diabetic ketoacidosis. Not recommended in NYHA class IV. Hypoglycaemia. Perform liver function tests prior to & during treatment at 3-mth intervals for the 1st yr & periodically thereafter. Routine care for diabetic patients & monitor for skin disorders. Not to be used in galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May affect ability to drive & use machines. Renal impairment or end-stage renal disease on haemodialysis. Not to be used in hepatic impairment & if AST or ALT increased >3 x upper limit of normal. Not to be used in pregnancy & lactation. Not recommended in childn & adolescents <18 yr.