Gamunex-C

Gamunex-C

human normal immunoglobulin

Manufacturer:

Grifols

Distributor:

DKSH
Concise Prescribing Info
Contents
Human Ig
Indications/Uses
Primary humoral immunodeficiency. Idiopathic thrombocytopenic purpura. Chronic inflammatory demyelinating polyneuropathy.
Dosage/Direction for Use
Primary humoral immunodeficiency 300-600 mg/kg IV every 3-4 wk. Idiopathic thrombocytopenic purpura 1 g/kg IV in 2 divided doses for 2 consecutive days or 0.4 g/kg IV for 5 consecutive days. Total dose: 2 g/kg. Chronic inflammatory demyelinating polyneuropathy Initial loading dose: 2 g/kg IV in divided doses over 2-4 consecutive days. Maintenance infusion: 1 g/kg IV over 1 day or 0.5 g/kg IV for 2 consecutive days every 3 wk.
Contraindications
Hypersensitivity. IgA deficient patients w/ antibodies against IgA. SC administration in patients w/ idiopathic thrombocytopenic purpura.
Special Precautions
Hyperproteinemia, increased serum viscosity & hyponatremia. Thrombotic events; assess baseline blood viscosity in patients at risk for hyperviscosity. Rapid infusion & high doses may cause aseptic meningitis syndrome. Monitor for signs & symptoms of hemolysis; pulmonary adverse reactions. Renal impairment. Pregnancy & lactation. Childn. Elderly ≥65 yr.
Adverse Reactions
Headache, cough, inj site reaction, nausea, pharyngitis & urticaria; fatigue, arthralgia & pyrexia; vomiting, fever, back pain & rash; chills, HTN, asthenia.
Drug Interactions
Heparin. Live vaccines. Dilution w/ saline.
ATC Classification
J06BA - Immunoglobulins, normal human ; Used in passive immunizations.
Presentation/Packing
Form
Gamunex-C inj (vial) 10%
Packing/Price
10 mL x 1's;100 mL x 1's;200 mL x 1's;25 mL x 1's;50 mL x 1's
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