Adult and children nasal drops: In the following cases this drug may only be used after carefully weighing the risk-to benefit ratio: Patients treated with monoamine oxidase inhibitors (MAO inhibitors, tricyclic antidepressants) and other drugs potentially increasing blood pressure.
Increased intraocular pressure, especially narrow-angle glaucoma.
Severe cardiovascular diseases (e.g. coronary heart disease, hypertension).
Metabolic disorders (e.g. hyperthyroidism, diabetes mellitus, porphyria).
Hyperplasia of the prostate.
Long-term use and overdosage are to be avoided. The efficacy of decongestant rhinological agents may be reduced (tachyphylaxis) with long-term use or overdose. This may lead to use of higher doses or to more frequent usage which, in turn, can result in permanent use. If long term use or overdose occurs, treatment should be discontinued immediately. Continuous use may cause nasal congestion due to reactive hyperaemia of the nasal mucosa (rebound effect) and chronic swelling of the nasal mucosa (rhinitis medicamentosa) as well as mucosal atrophy or rhinitis sicca. Rebound effects and tachyphylaxis should stop once use of the product is discontinued. Patients are advised to use for a maximum of 10 consecutive days to avoid rebound effect and drug induced rhinitis.
Medical supervision is indicated in patients with chronic rhinitis. Dosages higher than recommended may only be used under medical supervision.
Benzalkonium chloride: irritant, may cause skin reactions.
Infant nasal drops: Permanent use of decongestant rhinological agents may attenuate their effect. The abuse of local rhinological agents may cause mucosal atrophy and reactive hyperaemia with rhinitis medicamentosa.
Longer use of oxymetazoline may cause damage to the mucosal epithelium with inhibition of ciliary activity. This may possibly result in irreversible damage to the mucosa with rhinitis sicca.
Long-term use and overdosage are to be avoided.
The efficacy of decongestant rhinological agents may be reduced (tachyphylaxis) with long-term use or overdose. This may lead to use of higher doses or to more frequent usage which, in turn, can result in permanent use. If long term use or overdose occurs, treatment should be discontinued immediately.
As with all nasal decongestant, Iliadin should not be used for longer than 10 consecutive days.
Effects on ability to drive and use machines: No impairment is to be expected if used as recommended. Systemic effects with involvement of the cardiovascular or central nervous system cannot be excluded after prolonged administration or intake of oxymetazoline containing cold remedies in dose higher than recommended. In these cases the ability to drive a vehicle or operate machinery can be impaired.