Indocyanine green


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : IV Assessment of hepatic function 500 mcg/kg. Parenteral Assessment of cardiac output 5 mg inj via cardiac catheter. Several doses are given to obtain a number of dilution curves. Max: 2 mg/kg/dose.
Dosage Details
Intravenous
Assessment of hepatic function
Adult: 500 mcg/kg. Patient should be in a fasting basal state.

Parenteral
Assessment of cardiac output
Adult: 5 mg inj rapidly into the cardiac catheter. Give several doses to obtain a number of dilution curves. Max dose: 2 mg/kg.
Child: 2.5 mg/dose. Infants: 1.25 mg/dose. Give several doses to obtain a number of dilution curves. Max dose: 2 mg/kg.
Incompatibility
Reduced absorption peak with preps containing reducing agents e.g. bisulfite, metabisulfite, borohydrate.
Special Precautions
Caution in patients with iodide allergy as commercial prep may contain sodium iodide. Pregnancy and lactation.
Adverse Reactions
Urticaria, pruritus, headache, discolouration of faeces, diaphoresis.
Potentially Fatal: Anaphylaxis.
IV/Parenteral: C
Drug Interactions
Half-life may be decreased with phenobarbital, phenylbutazone, primidone, phenytoin, opiate derivatives (in addicts), haloperidol, nitrofurantoin, sulthiame. May impair hepatic excretion of sulfobromophthalein sodium.
Lab Interference
Do not perform radioactive iodine studies for at least 1 wk after use.
Action
Description: The use of indocyanine green as a dye is based on its distribution in the body.
Pharmacokinetics:
Distribution: Protein-binding: 95% to albumin.
Excretion: Via bile (unchanged); 2.2-3 min (elimination half-life).
Storage
Store at room temperature of 15-25°C (59-77°F).
Disclaimer: This information is independently developed by MIMS based on Indocyanine green from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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