IXIME is indicated in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: Uncomplicated Urinary Tract Infections caused by Escherichia coli & Proteus mirabilis.
Otitis Media caused by Haemophilus influenzae (β lactamase positive & negative strains), Moraxella catarrhalis (most of which are β lactamase positive) and Streptococcus pyogenes.
Pharyngitis and Tonsillitis caused by Streptococcus pyogenes.
Note: Penicillin is the usual drug of choice in the treatment of Streptococcus pyogenes infections, including the prophylaxis of Rheumatic Fever. Cefixime is generally effective in the eradication of Streptococcus pyogenes from the nasopharynx, however, data establishing the efficacy of Cefixime in the subsequent prevention of Rheumatic Fever are not available.
Acute Bronchitis and Acute Exacerbations of Chronic Bronchitis, caused by Streptococcus pneumoniae & Haemophilus influenzae (β lactamase positive and negative strains).
Uncomplicated Multidrug Resistant and Quinolone Resistant Typhoid Fever caused by Salmonella typhi.
Uncomplicated Gonorrhea (cervical/urethral) caused by both Penicillinase and Non Penicillinase Producing Strains of Neisseria gonorrhoeae.