Before therapy with Cefixime is instituted, careful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cephalosporins, penicillins or other drugs.
FC tab: If this product has to be given to penicillin sensitive patients, caution should be exercised because cross hypersensitivity among β lactam antibiotics has been clearly documented and may occur in up to 10% of patients with a history of penicillin allergy.
If an allergic reaction to cefixime occurs, discontinue the drug.
Serious acute hypersensitivity reactions may require treatment with emergency measures including oxygen, intravenous fluids, intravenous antihistamines, corticosteroids, pressor amines and airway management as clinically indicated.