Lofral Dosage & Drug Information

Concise Prescribing Info

Contents

Amlodipine besylate

Indications/Uses

Essential HTN, MI or angina (unstable & vasospasm or Prinzmetal).

Dosage/Direction for Use

HTN Initially 2.5-10 mg daily. Maintenance: 5-10 mg daily. Angina pectoris Initially 5-10 mg daily. Maintenance: 10 mg daily.

Administration

May be taken with or without food.

Contraindications

Known hypersensitivity to dihydropyridines.

Special Precautions

Severe left ventricular dysfunction, obstructive hypertrophic cardiomyopathy, oedema, increased intracranial pressure. Hepatic impairment. Pregnancy & lactation. Elderly.

Adverse Reactions

Peripheral oedema. Flushing, palpitations; headache, fatigue, dizziness, somnolence; dermatitis, rash, pruritus, urticaria; sexual dysfunction; cramps.

View ADR Monitoring Form

Drug Interactions

Cyclosporin, fentanyl.

MIMS Class

Calcium Antagonists / Anti-Anginal Drugs

ATC Classification

C08CA01 - amlodipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.

Regulatory Classification

Presentation/Packing

Form

Lofral tab 10 mg

Packing/Price

30's

Form

Lofral tab 5 mg

Packing/Price

30's

Lofral

amlodipine

Manufacturer:

Acino Switzerland

Distributor:

Mepharm