vaccine, mmr


Merck Sharp & Dohme


Zuellig Pharma
Concise Prescribing Info
Live MMR virus vaccine
Simultaneous vaccination against measles, mumps & rubella in individuals ≥12 mth.
Dosage/Direction for Use
0.5 mL SC into the outer aspect of the upper arm. Do not give Ig concurrently w/ M-M-R II. Recommended vaccination schedule Individual 1st vaccinated at ≥12 mth should be revaccinated at 4-6 yr or 11-12 yr. Measles outbreak schedule Infant who are vaccinated between 6-12 mth in an outbreak situation should receive 2nd dose of M-M-R II at 15 mth, followed by revaccination at 4-6 yr or 11-12 yr.
Hypersensitivity including gelatin. Anaphylactic or anaphylactoid reactions to neomycin. Febrile resp illness or other active febrile infection. Active untreated TB. Patients receiving immunosuppressive therapy. Blood dyscrasias, leukemia, lymphomas of any type, or other malignant neoplasms affecting the bone marrow or lymphatic systems. Primary & acquired immunodeficiency states including patients who are immunosuppressed in association w/ AIDS or other clinical manifestations of infection w/ HIV; cellular immune deficiencies; hypo- & dysgammaglobulinemic states. Measles inclusion body encephalitis, pneumonitis & death as direct consequence of disseminated measles vaccine virus infection has been reported in severely immunocompromised individuals inadvertently vaccinated w/ measles-containing vaccine. Family history of congenital or hereditary immunodeficiency until immune competence of potential vaccine recipient is demonstrated. Pregnancy. Avoid pregnancy for 1 mth following vaccination.
Special Precautions
Not to be inj IV. History of anaphylactic, anaphylactoid or other immediate reactions subsequent to egg ingestion. Patients w/ individual or family histories of convulsion, history of cerebral injury or other condition in which stress due to fever should be avoided. Current thrombocytopenia. HIV-infected or immunosuppressed patients. Not to be used during pregnancy. Lactation. Infants <12 mth.
Adverse Reactions
Inj site burning &/or stinging of short duration.
Drug Interactions
Interfered immune response w/ Ig. Defer vaccination for ≥3 mth following human Ig & blood or plasma transfusions.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07BD52 - measles, combinations with mumps and rubella, live attenuated ; Belongs to the class of morbilli viral vaccines.
M-M-R II vaccine (inj) (single-dose vial)
(single dose) 0.5 mL x 1's
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