Marcaine 0.5% Adrenaline

Marcaine 0.5% Adrenaline

Manufacturer:

Aspen

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Per mL Bupivacaine HCl 5 mg, adrenaline 5 mcg
Indications/Uses
Surgical anesth: Epidural block for surgery & field block (minor & major nerve blocks & infiltration). Analgesia: Continuous epidural infusion or intermittent bolus epidural administration for analgesia in post-op or labour pain & field block (minor nerve block & infiltration).
Dosage/Direction for Use
Contraindications
Hypersensitivity to amide-type local anesth. IV regional anesth (Bier's block); epidural anesth in patients w/ pronounced hypotension eg, cardiogenic or hypovolemic shock.
Special Precautions
Not to be used as IA continuous infusion. Impaired CV function; 2nd- or 3rd-degree AV block; severe or untreated HTN, thyrotoxicosis, ischemic heart disease, cerebrovascular insufficiency, advanced diabetes & other adrenaline-exacerbated conditions; use in peripheral body parts eg, fingers or body parts having low blood supply. May cause allergic reactions due to Na metabisulphite. Insert IV cannula before local anaesth. Retro- & peribulbar inj, paracervical block. Epidural anaesth can lead to hypotension & bradycardia; reduce risk of such effects by eg, vasopressor inj. Inadvertent intravascular administration. High-dose use. Concomitant use w/ class III antiarrhythmics. May affect ability to drive & use machines. Severe hepatic or renal impairment. Pregnancy & lactation. Elderly.
Adverse Reactions
Hypotension; nausea. Paraesthesia, dizziness; bradycardia; HTN; vomiting; urinary retention.
Drug Interactions
Additive systemic toxic effects w/ other local anaesth or structurally-similar agents ie, class IB anti-arrhythmics. Enhanced adrenaline pressor effect w/ non-selective β-blockers eg, propranolol. Severe cardiac arrhythmias w/ halothane during general anaesth. Marked increased BP w/ TCAs, ergot-type oxytocic drugs. Decreased/inhibited adrenaline pressor effect w/ ohenothiazine & butyrophenone derivatives. Class III anti-anrrhythmics eg, amiodarone.
ATC Classification
N01BB51 - bupivacaine, combinations ; Belongs to the class of amides. Used as local anesthetics.
Presentation/Packing
Form
Marcaine 0.5% Adrenaline inj
Packing/Price
20 mL x 5 × 1's
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