Medroxyprogesterone - oral

Patient Medicine Information
Why do I need this medicine?
Medroxyprogesterone is used to treat abnormal vaginal bleeding (due to hormonal imbalance) and absence of menstruation.

This medicine may be used to treat other condition as decided by your doctor.
How do I take this medicine?
Take Medroxyprogesterone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine with or without food. However, incidence of stomach upset increases as dose increase. You may take it with food if necessary. Try to take it at the same time each day.

Medroxyprogesterone must be taken regularly for it to be effective. Continue taking it even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • blood clot disorder e.g. formation of blood clots in your legs or lungs
  • recent heart attack
  • recent stroke
  • liver disease or history of liver disease
  • known, suspected or a history of breast cancer
  • unexplained or unusual vaginal bleeding
  • porphyria (an inherited disorder that may cause skin or nerve problems)
as this medicine may not be suitable for you.

Do not take Medroxyprogesterone if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Medroxyprogesterone may cause harm to your unborn child. You must use proven birth control methods while taking this medicine.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • epilepsy (fits or seizures)
  • asthma
  • migraine
  • heart disease or risk factors for heart disease e.g. high blood pressure, high cholesterol, diabetes, obesity, smoking, history of blood clot disorder
  • kidney disease
  • diabetes
  • history of depression
Let your doctor know if you are breastfeeding.

If you are going for any laboratory tests, inform your doctor that you are being treated with Medroxyprogesterone as it can interfere with certain tests.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Your doctor may need to do routine tests while you are being treated with this medicine.
What side effects could I experience?
Medroxyprogesterone may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Medroxyprogesterone may cause any of the following side effects: headache, nausea, vomiting, bloating, nervousness, difficulty sleeping, acne, hair loss, itching, rash, tiredness, increased weight, breast pain, breast tenderness, decreased sex drive and vaginal bleeding between periods.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • abnormal vaginal bleeding
  • sudden partial or complete vision loss
  • yellowing of skin or eyes
  • pain and swelling in your arms and legs
  • shortness of breath and chest pain
  • severe headache
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for Parkinson’s disease (disorder that affects movement of a person, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking) e.g. bromocriptine
  • blood-thinning medicines e.g. warfarin
  • medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenobarbital, phenytoin
  • medicines for tuberculosis or TB e.g. rifampicin, rifabutin
  • herbal medicines e.g. St John’s wort
  • medicines for HIV infection e.g. ritonavir, nelfinavir, nevirapine, efavirenz
This list does not include all medicines that may interact with Medroxyprogesterone.

Always notify your doctor or pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on medroxyprogesterone - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by
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