Medroxyprogesterone is used to prevent pregnancy.
It may also be used in the management of pain associated with endometriosis (a disease in which tissues that lines the uterus grows outside of it).
This medicine may be used to treat other conditions as decided by your doctor.
Medroxyprogesterone is to be given intramuscularly (into the muscle, usually in the arms or buttocks).
Your doctor or nurse will administer the injection for you.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of treatment depending on the type of your condition.
Medroxyprogesterone must be administered on a regular interval for it to be effective. Do not stop receiving the treatment unless instructed by your doctor.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Medroxyprogesterone.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
Alert your doctor if you have the following conditions:
- history of or existing blood clot disorder
- have had a stroke
- known, suspected, or a history of breast cancer
- unexplained or unusual vaginal bleeding
- liver disease
as Medroxyprogesterone may not be suitable for you.
Do not use Medroxyprogesterone if you are pregnant. If you become pregnant while being treated with this medicine, alert your doctor immediately. Medroxyprogesterone may cause harm to your unborn child.
Inform your doctor if you have the following conditions:
- epilepsy (fits or seizures)
- risk factors for osteoporosis (thinning and weakening of bones) e.g. bone disease, regular alcohol intake and smoking, eating disorder, family history of osteoporosis
- family history of breast cancer
- high blood pressure
- heart problems
- history of or existing depression
- kidney disease
Let your doctor know if you are breastfeeding.
If you are going for any laboratory tests, inform your doctor that you are being treated with Medroxyprogesterone as it may interfere with certain tests.
For as long as you are using this medicine, you may need to have certain tests to check your body’s response to the medicine. Your doctor will advise you about how often you need to have these tests.
Medroxyprogesterone may cause any of the following side effects: headache, dizziness, nausea, stomach pain or discomfort, bloating, tiredness, back pain, nervousness, difficulty sleeping, acne, hair loss, itching, rash, weight gain or loss, breast tenderness, decreased sexual drive, and vaginal discharge.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- unexpected or unusual vaginal bleeding
- changes in your eyesight
- yellowing of skin or eyes
- shortness of breath, chest pain
- severe headache
- rashes, breathlessness, swelling of the face, eyes or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for fits or seizures e.g. carbamazepine, phenobarbital, phenytoin
- rifampicin (medicine for TB [infection known as tuberculosis])
- medicines for HIV infection e.g. nevirapine, efavirenz
- aminoglutethimide (medicine used for Cushing syndrome [a disorder that occurs when the body makes too much hormone called cortisol])
- St. John’s wort (herbal medicine)
This list does not include all medicines that may interact with Medroxyprogesterone.
Always notify your doctor or pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.