Miltefosine


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Visceral Leishmaniasis 100-150 mg/day for 28 days. Topical Mycosis fungoides; Skin metastases of breast cancer As 6% soln: Apply 1-2 times/day.
Dosage Details
Oral
Visceral leishmaniasis
Adult: 100-150 mg daily for 28 days.

Topical/Cutaneous
Mycosis fungoides, Skin metastases of breast cancer
Adult: 6% solution applied 1-2 times daily.
Contraindications
Pregnancy, lactation, concurrent radiation therapy.
Special Precautions
Metastases grown over breast implants.
Adverse Reactions
Oral: leukocytosis; thrombocytosis; GI irritation, nausea, vomiting, diarrhoea, constipation; ocular, hepatic, renal toxicity. Topical: pruritis; erythema; scaling; xerosis; tightness of the skin; dermatitis; pain; ulceration; necrosis.
Action
Description: Miltefosine is a phospholipid derivative thought to work by disrupting cell-membrane function.
Disclaimer: This information is independently developed by MIMS based on Miltefosine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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