Discontinue use at 1st appearance of skin rash, mucosal lesions or any other sign of hypersensitivity. Patients w/ history of GI disease; other risk factors associated w/ PUD eg, alcoholism, smoking, corticosteroid therapy; CV disease or risk factors for CV disease; decreased renal blood flow or vol; dehydration, CHF; recent major surgical procedures leading to hypovolaemia. May mask symptoms of an underlying infectious disease. Not to be taken by patients w/ galactose intolerance eg, galactosaemia. Not to be co-administered w/ other NSAIDs. Concomitant use w/ anticoagulants, diuretic, ACE inhibitor or AIIA. May affect ability to drive & use machines. Hepatic cirrhosis, nephrotic syndrome, overt renal disease; end-stage renal failure on haemodialysis. May impair fertility. Not recommended in women of childbearing potential. Not to be used in childn & adolescents. Elderly, frail or debilitated patients.