Cumulative dose: Up to 2,000 mg should be considered based on body Fe deficit. IV bolus inj Up to 500 mg administered at rate 250 mg/min up to 3 times wkly. IV drip infusion Cumulative dose: Up to 20 mg/kg single infusion. Doses up to 1,000 mg should be given >15 min; doses >1,000 mg should be given ≥30 min for not more than once wkly. HD patient May be given directly into venous limb of dialyser. Therapeutic response can be seen w/in few days.
View Monofer overdosage for action to be taken in the event of an overdose.
Contraindications
Hypersensitivity to other parenteral Fe products. Non-Fe deficiency anaemia (eg, haemolytic anaemia), Fe overload or disturbances in Fe utilisation (eg, haemochromatosis, haemosiderosis), decompensated liver cirrhosis, hepatitis.
Hypersensitivity. Not to be used in patients w/ ongoing bacteraemia. History of severe asthma, eczema or other atopic allergy. Patients w/ immune or inflammatory conditions eg, SLE, RA; acute or chronic infection. Avoid too rapid IV inj. 1st trimester of pregnancy. Not recommended in childn & adolescents <18 yr.
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