Nadifloxacin


Concise Prescribing Info
Indications/Uses
Acne vulgaris.
Dosage/Direction for Use
Adult : Topical As 1% cream/gel: Apply to affected area bid.
Dosage Details
Topical/Cutaneous
Acne vulgaris
Adult: As 1% cream/gel: Apply to affected area bid. Discontinue treatment if desired effect is not achieved after 4 weeks.
Contraindications
Hypersensitivity to nadifloxacin or other fluoroquinolones.
Adverse Reactions
Skin and subcutaneous tissue disorders: Itching and erythema at application sites, pruritus, redness, flushing, feeling of facial warmth, papules, contact dermatitis, dry skin.
Action
Description: Nadifloxacin, a synthetic fluoroquinolone anti-infective agent, acts by inhibiting the bacterial DNA gyrase which is involved in DNA synthesis and replication, thus inhibiting bacterial multiplication
Pharmacokinetics:
Absorption: Time to peak plasma concentration: 8 hours (post-final dosing).
Excretion: Via urine (approx 0.09%). Elimination half-life: 19.4 hours.
Chemical Structure

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Storage
Store below 30°C.
MIMS Class
ATC Classification
D10AF05 - nadifloxacin ; Belongs to the class of topical antiinfective preparations used in the treatment of acne.
Disclaimer: This information is independently developed by MIMS based on Nadifloxacin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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