Discontinue use if localized nose & pharynx infections develop. Recent nasal septal ulcers, surgery or trauma. Cushing's syndrome, Cushingoid features, adrenal suppression, cataract, glaucoma, psychomotor hyperactivity, sleep disorders, anxiety, depression or aggression. Visual disturbance. Transferring patients from systemic treatment. Additional therapy during period of stress or elective surgery. High doses & prolonged use. May cause skin irritation due to benzalkonium Cl. Closely monitor patients w/ change in vision or history of IOP, glaucoma &/or cataracts. Pregnancy & lactation. Growth retardation in childn & adolescents. Not recommended in childn <2 yr.