NeoMercazole

NeoMercazole

carbimazole

Manufacturer:

A. Menarini

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Carbimazole
Indications/Uses
Hyperthyroidism. Prep for thyroidectomy in hyperthyroidism. Therapy prior to & post radio-iodine treatment.
Dosage/Direction for Use
Adult Initially 20-60 mg titrated until euthyroidism. Maintenance: 5-15 mg daily taken as single dose. Blocking-replacement regimen Initially 20-60 mg daily + supplemental l-thyroxine 50-150 mcg daily for at least 6-18 mth. Childn Initially 15 mg daily.
Administration
May be taken with or without food: Take consistently w/ or w/o meals.
Contraindications
Hypersensitivity. Serious, preexisting haematological conditions. Severe hepatic insufficiency. Pregnancy & lactation.
Special Precautions
Discontinue use if onset of sore throats, bruising or bleeding, mouth ulcers, fever, malaise, neutropenia occur. Monitor white cell counts in clinical evidence of infection. Perform liver function tests following onset of hepatic disorder (upper abdomen pain, anorexia, general pruritus). Regularly perform complete blood count in confused patients or w/ poor memory. Intrathoracic goitre. Temporary discontinue at the time of radio-iodine administration. Concomitant use w/ propylthiouracil. Mild to moderate hepatic insufficiency. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Women of childbearing potential. Elderly ≥65 yr.
Adverse Reactions
Nausea, headache, arthralgia, mild gastric distress, skin rashes, pruritus.
Drug Interactions
Intensified anticoagulants effects. Increased serum levels & toxicity of theophylline. Concurrent administration w/ drugs inducing agranulocytosis.
MIMS Class
ATC Classification
H03BB01 - carbimazole ; Belongs to the class of sulfur-containing imidazole derivative agents. Used in the management of thyroid diseases.
Presentation/Packing
Form
NeoMercazole tab 5 mg
Packing/Price
100's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in