Neomycin + Dexamethasone + Acetic acid

Generic Medicine Info
Indications and Dosage
Otitis externa
Adult: 1 spray (60 mg) to each affected ear tid. Continue treatment until 2 days after symptoms have disappeared. Discontinue if there is no clinical improvement after 7 days.
Child: ≥2 yr Same as adult dose.
Hypersensitivity to neomycin sulfate, dexamethasone or glacial acetic acid. Known or suspected perforation of tympanic membrane or where a tympanostomy tube (grommet) is in situ.
Special Precautions
Childn. Pregnancy and lactation.
Adverse Reactions
Skin sensitisation or hypersensitivity leading to burning, stinging, irritation, itching and dermatitis.
Description: Neomycin is a broad spectrum antibiotic while dexamethasone is a topical anti-inflammatory steroid. Acetic acid assist in the control of bacterial infection by producing a low pH.
Distribution: Widely distributed in the surface.
Chemical Structure

Chemical Structure Image

Source: National Center for Biotechnology Information. PubChem Database. Neomycin, CID=8378, (accessed on Jan. 21, 2020)

Chemical Structure Image

Source: National Center for Biotechnology Information. PubChem Database. Dexamethasone, CID=5743, (accessed on Jan. 20, 2020)

Chemical Structure Image
Acetic acid

Source: National Center for Biotechnology Information. PubChem Database. Acetic acid, CID=176, (accessed on Jan. 22, 2020)

Store at or below 25°C. Do not freeze.
MIMS Class
Ear Antiseptics with Corticosteroids
Joint Formulary Committee. Dexamethasone with Glacial Acetic Acid and Neomycin Sulfate . British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. Accessed 06/04/2016.

Otomize (Forest Laboratories UK Limited). MHRA. . Accessed 06/04/2016.

Disclaimer: This information is independently developed by MIMS based on Neomycin + Dexamethasone + Acetic acid from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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