Concise Prescribing Info
Pain & inflammation associated w/ cataract surgery. Reduce risk of post-op macular oedema associated w/ cataract surgery in diabetic patients.
Dosage/Direction for Use
Instill 1 drop to affected eye(s) tds 1 day prior to cataract surgery, continue on the day of surgery until 1st 2 wk post-op. Reduce risk of post-op macular oedema associated w/ cataract surgery in diabetic patient Instill 1 drop into conjunctival sac of affected eye(s) tds 1 day prior to surgery, continue on the day of surgery & up to 60 days post-op. Additional drop should be administered 30-120 min prior to surgery.
Hypersensitivity to nepafenac or other NSAIDs.
Special Precautions
Discontinue use if corneal epithelial breakdown is evident. Patients w/ repeat &/or complex ocular surgeries, corneal denervation & epithelial defects, DM, ocular surface diseases, dry eye or RA; known bleeding tendencies or receiving drugs prolonging bleeding time. Punctate keratopathy, toxic ulcerative keratopathy & eye irritation due to benzalkonium Cl. May mask acute ocular infection. Avoid wearing contact lens during treatment. Avoid contact of dropper tip w/ eyelid or any surfaces. Cross sensitivity to acetylsalicylic acid, phenylacetic acid derivatives & other NSAIDs. Administer at least 5 min apart if >1 topical ophth medicinal product is used. Concomitant use of topical corticosteroids. Prolonged use. May affect ability to drive & use machines. Not recommended in women of childbearing potential not using contraception & during pregnancy. Lactation. Not recommended in ped patients.
Adverse Reactions
Uncommonly, keratitis, punctate keratitis, corneal epithelium defect, allergic conjunctivitis, eye pain, foreign body sensation in eyes, eyelid margin crusting.
Drug Interactions
Potential healing problems w/ topical steroids. Increased risk of hemorrhage w/ medications prolonging bleeding time.
MIMS Class
Ophthalmic Decongestants, Anesthetics, Anti-Inflammatories
ATC Classification
S01BC10 - nepafenac ; Belongs to the class of non-steroidal antiinflammatory agents. Used in the treatment of inflammation of the eye.
Nevanac ophth susp 0.1 %
5 mL x 1's
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