Nexium/Nexium MUPS

Nexium/Nexium MUPS Description





Zuellig Pharma
Full Prescribing Info
Nexium: Each vial contains esomeprazole 40 mg (as sodium salt).
Each vial contains 1 <mmol sodium.
Nexium MUPS: Each tablet contains: 20 mg or 40 mg esomeprazole (as magnesium trihydrate).
Excipients: Nexium 20 mg: Sucrose 28 mg. Nexium 40 mg: Sucrose 30 mg.
Nexium MUPS is a proton pump inhibitor. The active ingredient in Nexium MUPS is esomeprazole magnesium trihydrate, a substituted benzimidazole. Esomeprazole is the S-isomer of omeprazole. It is optically stable in vivo, with negligible conversion to the R-isomer. The chemical name is di-(S)-5-methoxy-2-[[4-methoxy-3,5-dimethyl-2-pyridinyl)methyl] sulfinyl] -1H- benzimidazole magnesium salt trihydrate.
Molecular formula: C34H36N6O6S2Mg·3H2O.
Molecular weight: 767.2 (trihydrate).
Excipients/Inactive Ingredients: Nexium: Disodium edetate, Sodium hydroxide (for pH adjustment).
Nexium MUPS: Glycerol monostearate 40-55, hyprolose, hypromellose, iron oxide (E 172) (Tablet 20 mg, reddish-brown CI 77491, yellow, CI 77492) (Tablet 40 mg, reddish-brown CI 77491), magnesium stearate, methacrylic acid ethyl acrylate copolymer (1:1) dispersion 30 percent, cellulose microcrystalline, synthetic paraffin, macrogols, polysorbate 80, crospovidone, sodium stearyl fumarate, sugar spheres (sucrose and maize starch), talc, titanium dioxide (E 171), triethyl citrate.
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