Dosing in constipation or where soft stool is considered of medical benefit: Adults: Starting dose: 15-45 ml. Maintenance dose: 15-30 ml.
Children (7-14 years): Starting dose: 15 ml. Maintenance dose: 10-15 ml.
Children (1-6 years): Starting dose: 5-10 ml. Maintenance dose: 5-10 ml.
Infant under 1 year: Starting dose: 5 ml. Maintenance dose: 5 ml.
Dosing in precoma and coma hepaticum (for adults only): Starting dose: 30-45 ml, three to four times daily.
The maintenance dose should be adjusted so that soft stools are produced 2-3 times daily.
The starting dose can be adjusted to the individual after reaching adequate treatment effect (maintenance dose). Several days (2-3 days) of treatment may be needed in some patients before treatment effect occurs.
During the therapy with laxatives it is recommended to drink sufficient amounts of fluids (1.5–2 litres, equal to 6-8 glasses) during the day.
Administration: Lactulose can be taken as a single daily dose or in two divided doses. Dose need to be taken in one swallow. It should not be held in the mouth for length of time.
Dosage will be adjusted to individual needs. NOPHALAC is best taken at the same time each day, preferably at breakfast time.
Nophalac can be taken diluted or undiluted.