Nurofen Express

Nurofen Express

ibuprofen

Manufacturer:

RB (Health)

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Ibuprofen lysine
Indications/Uses
Pain relief eg, headache, migraine, dental, period, rheumatic & muscular pain & backache. Relieves fever associated w/ cold & flu.
Dosage/Direction for Use
342 mg Adult, elderly & childn >12 yr 1 or 2 caplets up to tds w/ 4 hr intervals. Max: 6 caplets/24 hr. 684 mg Adult, elderly & childn >12 yr 1 caplet up to tds w/ 4 hr intervals. Max: 3 caplets/24 hr.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to ibuprofen, aspirin or other NSAIDs. Active or history of peptic ulceration. Patients who undergone CABG surgery & revascularization procedures. Severe heart, renal or hepatic failure. Last trimester of pregnancy.
Special Precautions
Discontinue use at 1st appearance of skin rash, mucosal lesions or any hypersensitivity. Previous history of bronchial asthma or allergic disease. SLE & mixed connective tissue disease. Renal impairment, hepatic dysfunction. HTN, heart failure. Long-term high doses treatment. History of GI disease eg, ulcerative colitis, Crohn's disease. Exfoliative dermatitis, Stevens-Johnson syndrome. Concomitant oral corticosteroids, anticoagulants, SSRIs, anti-platelet drugs. Avoid concomitant NSAIDs including COX-2 selective inhibitors. Avoid during 1st 6 mth & not to be used in last trimester of pregnancy. Lactation. Elderly.
Adverse Reactions
Stomach discomfort or pain, indigestion, nausea, GI intolerance & bleeding, stomach ulcer, activation of peptic ulcer, black tarry stools, rashes or worsening of asthma, liver & kidney problems, headache & dizziness.
Drug Interactions
Inhibited effect of low-dose aspirin on platelet aggregation. Increased risk of adverse effect w/ other NSAIDs including COX-2 selective inhibitors. Increased risk of GI ulceration or bleeding w/ corticosteroids, anti-platelet agents, SSRIs. Diminished effect of antihypertensives. Increased nephrotoxicity by diuretics, ciclosporin. tacrolimus. Enhanced anticoagulant effect. Increased plasma glycoside, lithium, methotrexate levels. Reduced effect of mifepristone. Increased hematological toxicity w/ zidovudine. Increased risk of convulsions associated w/ quinolones.
ATC Classification
M01AE01 - ibuprofen ; Belongs to the class of propionic acid derivatives of non-steroidal antiinflammatory and antirheumatic products.
Presentation/Packing
Form
Nurofen Express FC caplet 684 mg
Packing/Price
12's
Form
Nurofen Express FC caplet 342 mg
Packing/Price
12's
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