Octopamine


Concise Prescribing Info
Contraindications
Pre-existing hypertension; occlusive vascular disease; phaeochromocytoma; angle-closure glaucoma (eye drops); hypersensitivity; cardiac arrhythmias.
Special Precautions
CV diseases; hyperthyroidism; DM; Parkinson's disease; elderly; pregnancy, lactation, prostate disorders.
Adverse Reactions
CNS effects; GI disturbances; epigastric pain; CV disorders; difficulty in micturition with urinary retention; dyspnoea; hyperglycaemia; sweating; hypersalivation; weakness, tremors; coldness of extremities; hypokalaemia, tachycardia, reflex bradycardia. Gangrene, tissue necrosis and sloughing (extravasation), especially when used in addition to local anaesthetics.
Drug Interactions
May antagonise effects of antihypertensives, guanethidine. Increased risk of ventricular fibrillation with inhalational anaesthetics. Pressor effects may be enhanced by ergot alkaloids or oxytocin. Additive toxicity may occur with antiparkinsonian drugs.
Potentially Fatal: Severe hypertension with MAOIs and other sympathomimetics.
Action
Description: Octopamine is a sympathomimetic with predominantly α-adrenergic activity used in the treatment of hypotensive states.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Octopamine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in