Oxiconazole


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : Topical Tinea corporis; Tinea cruris; Tinea pedis As 1% cream/lotion: Apply 1-2 times/day. Duration: 2 wk (tinea corporis and tinea cruris); 1 mth (tinea pedis). Pityriasis versicolor As 1 % cream: Apply once daily for 2 wk.
Dosage Details
Topical/Cutaneous
Pityriasis versicolor
Adult: As 1% cream: Apply to affected areas once daily for 2 wk.

Topical/Cutaneous
Tinea corporis, Tinea cruris, Tinea pedis
Adult: As 1% cream or lotion: Apply to affected and immediately surrounding areas 1-2 times daily. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis.
Contraindications
Hypersensitivity.
Special Precautions
Pregnancy and lactation.
Adverse Reactions
Pruritus, burning, irritation, stinging, erythema, rash, folliculitis, papules, nodules, maceration, fissuring, scaling, tingling, pain, dyshidrotic eczema, contact dermatitis.
Patient Counseling Information
Avoid contact w/ eyes or vagina.
Action
Description: Oxiconazole, a synthetic azole antifungal, is usually fungistatic but may be fungicidal in high concentrations. It exerts its antifungal activity by interfering w/ ergosterol synthesis and altering cellular membranes. It also has some antibacterial activity against aerobic gm+ve organisms.
Pharmacokinetics:
Absorption: Absorbed in each dermis layer. Very low systemic absorption.
Distribution: To each dermis layer.
Excretion: Via urine (<0.3%).
Chemical Structure

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Storage
Store between 15-30°C.
Disclaimer: This information is independently developed by MIMS based on Oxiconazole from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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