Oxyphenonium


Concise Prescribing Info
Contraindications
Urinary outflow obstruction, paralytic ileus, myasthenia gravis.
Special Precautions
Children; elderly; benign prostatic hyperplasia; acute MI, cardiac failure, hypertension, thyrotoxicosis; pregnancy and lactation; fever; angle-closure glaucoma.
Adverse Reactions
Dryness of mouth, difficulty in talking/swallowing; reduced bronchial secretions; blurring of vision, photophobia; bradycardia followed by tachycardia and arrhythmias; urinary retention, constipation, vomiting, nausea; confusion and giddiness.
Potentially Fatal: Arrhythmias (especially after MI).
Drug Interactions
Reduced gastric motility interferes with absorption of other drugs. Effects potentiated by other antimuscarinics including amantadine, some antihistamines, phenothiazines and TCA.
Action
Description: Oxyphenonium is a quarternary ammonium antimuscarinic.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Oxyphenonium from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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