Do not use the pen without proper training from your doctor or nurse.
Start by checking your pen to make sure that it contains Ozempic 0.25 mg, 0.5 mg or 1 mg then look at the illustrations below to get to know the different parts of your pen and needle.
If you are blind or have poor eyesight and cannot read the dose counter on the pen, do not use this pen without help.
Get help from a person with good eyesight who is trained to use the Ozempic pre-filled pen.
0.25 mg or 0.5 mg: Your pen is a pre-filled dial-a-dose pen. It contains 2 mg of semaglutide, and you can select doses of 0.25 mg or 0.5 mg.
1 mg: Your pen is a pre-filled dial-a-dose pen. It contains 4 mg of semaglutide, and you can only select doses of 1 mg.
Your pen is designed to be used with NovoFine and NovoTwist disposable needles up to a length of 8 mm.
NovoFine Plus needles are included in the pack.
1. Prepare your pen with a new needle: Check the name and coloured label of your pen, to make sure that it contains Ozempic. This is especially important if you take more than one type of injectable medicine. Using the wrong medicine could cause severe harm to your health.
Pull off the pen cap.
Check that the solution in your pen is clear and colourless. Look through the pen window. If the solution looks cloudy or coloured, do not use the pen.
Take a new needle and tear off the paper tab. If the paper tab is broken, do not use the needle, as sterility is not guaranteed.
Push the needle straight onto the pen. Turn until it is on tight.
Pull off the outer needle cap and keep it for later. You will need it after the injection, to safely remove the needle from the pen.
Pull off the inner needle cap and throw it away. If you try to put it back on, you may accidentally stick yourself with the needle.
A drop of solution may appear at the needle tip. This is normal, but you must still check the flow, if you use a new pen for the first time. See step 2 'Check the flow'.
Do not attach a new needle to your pen until you are ready to take your injection.
Always use a new needle for each injection.
This reduces the risk of blocked needles, contamination, infection and inaccurate dosing.
Never use a bent or damaged needle.
2. Check the flow: Before your first injection with each new pen, check the flow. If your pen is already in use, go to step 3 'Select your dose'.
Turn the dose selector until the dose counter shows the flow check symbol (
Hold the pen with the needle pointing up.
Press and hold in the dose button until the dose counter returns to 0. The 0 must line up with the dose pointer. A drop of solution should appear at the needle tip.
A small drop may remain at the needle tip, but it will not be injected.
If no drop appears, repeat step 2 'Check the flow' up to 6 times. If there is still no drop, change the needle and repeat step 2 'Check the flow' once more.
If a drop still does not appear, dispose of the pen and use a new one.
Always make sure that a drop appears at the needle tip before you use a new pen for the first time. This makes sure that the solution flows.
If no drop appears, you will not inject any medicine even though the dose counter may move. This may indicate a blocked or damaged needle.
If you do not check the flow before your first injection with each new pen, you may not get the prescribed dose and the intended effect of Ozempic.
3. Select your dose: 0.25 mg or 0.5 mg: Turn the dose selector until the dose counter shows your prescribed dose (0.25 mg or 0.5 mg). If you select the wrong dose, you can turn the dose selector forwards or backwards to the correct dose.
The dose selector changes the dose. Only the dose counter and dose pointer will show how many mg you select per dose.
The dose selector clicks differently when turned forwards, backwards or past the number of mg left. Do not count the pen clicks.
Always use the dose counter and the dose pointer to see how many mg you have selected before injecting this medicine.
Do not count the pen clicks.
The selected dose in the dose counter must line up precisely with the dose pointer to ensure that you get a correct dose.
1 mg: Turn the dose selector to select 1 mg. Keep turning until the dose counter stops and shows 1 mg.
Only the dose counter and dose pointer will show that 1 mg has been selected.
The dose selector clicks differently when turned forwards, backwards or past 1 mg. Do not count the pen clicks.
Always use the dose counter and the dose pointer to see that 1 mg has been selected before injecting this medicine.
Do not count the pen clicks.
1 mg in the dose counter must line up precisely with the dose pointer to ensure that you get a correct dose.
How much solution is left: 0.25 mg or 0.5 mg: To see how much solution is left, use the dose counter: Turn the dose selector until the dose counter stops. If it shows 0.5, at least 0.5 mg is left in your pen. If the dose counter stops before 0.5 mg, there is not enough solution left for a full dose of 0.5 mg.
1 mg: To see how much solution is left, use the dose counter: Turn the dose selector until the dose counter stops. If it shows 1, at least 1 mg is left in your pen.
If the dose counter stops before 1 mg, there is not enough solution left for a full dose of 1 mg.
If there is not enough solution left in your pen for a full dose, do not use it. Use a new Ozempic pen.
4. Inject your dose: Insert the needle into your skin as your doctor or nurse has shown you.
Make sure you can see the dose counter. Do not cover it with your fingers. This could interrupt the injection.
Press and hold down the dose button until the dose counter shows 0. The 0 must line up with the dose pointer. You may then hear or feel a click.
Keep the needle in your skin after the dose counter has returned to 0 and count slowly to 6. This is to make sure that you get your full dose.
If the needle is removed earlier, you may see a stream of solution coming from the needle tip. If so, the full dose will not be delivered.
Remove the needle from your skin. If blood appears at the injection site, press lightly. Do not rub the area.
You may see a drop of solution at the needle tip after injecting. This is normal and does not affect your dose.
Always watch the dose counter to know how many mg you inject. Hold the dose button down until the dose counter shows 0.
How to identify a blocked or damaged needle: If 0 does not appear in the dose counter after continuously pressing the dose button, you may have used a blocked or damaged needle.
In this case, you have not received any medicine - even though the dose counter has moved from the original dose that you have set.
How to handle a blocked needle: Change the needle as described in step 5 'After your injection' and repeat all steps starting with step 1 'Prepare your pen with a new needle'. Make sure you select the full dose you need.
Never touch the dose counter when you inject. This can interrupt the injection.
5. After your injection: Lead the needle tip into the outer needle cap on a flat surface without touching the needle or the outer needle cap.
Once the needle is covered, carefully push the outer needle cap completely on.
Unscrew the needle and dispose of it carefully in accordance with local guidelines. Ask your doctor, nurse or pharmacist about sharps disposal.
Put the pen cap on your pen after each use to protect the solution from light.
Always dispose of the needle after each injection to ensure convenient injections and prevent blocked needles. If the needle is blocked, you will not inject any medicine.
When the pen is empty, throw it away without a needle on as instructed by your doctor, nurse, pharmacist or local authorities.
Never try to put the inner needle cap back on the needle. You may stick yourself with the needle.
Always remove the needle from your pen immediately after each injection.
This reduces the risk of blocked needles, contamination, infection, leakage of solution and inaccurate dosing.
Further important information: Always keep your pen and needles out of the sight and reach of others, especially children.
Never share your pen or your needles with other people.
Caregivers must be very careful when handling used needles to prevent needle injury and cross-infection.
Caring for your pen: Treat your pen with care. Rough handling or misuse may cause inaccurate dosing. If this happens you might not get the intended effect of this medicine.
Do not inject Ozempic which has been frozen. If you do that, you might not get the intended effect of this medicine.
Do not inject Ozempic which has been exposed to direct sunlight. If you do that, you might not get the intended effect of this medicine.
Do not expose your pen to dust, dirt or liquid.
Do not wash, soak or lubricate your pen. If necessary, clean it with a mild detergent on a moistened cloth.
Do not drop your pen or knock it against hard surfaces. If you drop it or suspect a problem, attach a new needle and check the flow before you inject.
Do not try to refill your pen. Once empty, it must be disposed of.
Do not try to repair your pen or pull it apart.