Gastric malignancy. Increased risk of Clostridium difficile
-associated diarrhoea; GI infections caused by bacteria eg, Salmonella
osteoporosis-related hip, wrist or spine fractures. Hypomagnesaemia; subacute cutaneous lupus erythematosus. Vit B12
malabsorption due to long-term therapy (>3 yr). Not recommended w/ HIV PIs eg, atazanavir. Long-term use. Discontinue use at least 5 days prior to chromogranin A measurements. May affect ability to drive & use machines. Severe hepatic impairment. Not to be used during pregnancy. Lactation.