Perinace

Perinace

perindopril

Manufacturer:

Duopharma Manufacturing (Bangi)

Distributor:

Duopharma Marketing
Concise Prescribing Info
Contents
Perindopril erbumine
Indications/Uses
HTN & symptomatic heart failure.
Dosage/Direction for Use
HTN 4 mg once daily, may be increased to 8 mg once daily after 1 mth of treatment. Elderly Initially 2 mg once daily, may be progressively increased to 4 mg after 1 mth & then to 8 mg once daily if necessary. Symptomatic heart failure Initially 2 mg once daily, may be increased by 2 mg-increments at intervals of ≥2 wk to 4 mg once daily if tolerated.
Administration
Should be taken on an empty stomach.
Contraindications
History of angioedema associated w/ previous ACE inhibitor therapy; hereditary or idiopathic angioedema. 2nd or 3rd trimester of pregnancy.
Special Precautions
Vol or salt depletion, bilateral renal artery stenosis or artery stenosis to solitary kidney, ischaemic heart or cerebrovascular disease, mitral valve stenosis, left ventricular outflow obstruction (eg, aortic stenosis or hypertrophic cardiomyopathy), patients dialysed w/ high flux membranes. Patients undergoing major surgery or during anaesth w/ agents that cause hypotension. Uncontrolled DM. Renal impairment. Pregnancy & lactation.
Adverse Reactions
Headache, dizziness, vertigo, tinnitus, cough, dyspnoea, GI disorders, rash, pruritus, muscle cramps, asthenia.
Drug Interactions
Diuretics, K-sparing diuretics, K supplements or K-containing salt substitutes, lithium, NSAIDs, aspirin, antihypertensive agents & vasodilators, antidiabetic agents, TCAs, antipsychotics, anaesth, sympathomimetics.
ATC Classification
C09AA04 - perindopril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Perinace tab 4 mg
Packing/Price
3 × 10's
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